The Amsterdam Cohort Studies
The Amsterdam Cohort Study (ACS) is a prospective observational cohort study that focusses on HIV/ AIDS and other blood-borne infections, sexually transmittable infections (STI) and other infections. The ACS was initiated in 1984 and has mainly focused on men who have sex with men. Between 1984-2016, the study was expanded to include people who use drugs.
Initially focused on HIV/AIDS, the ACS has since expanded to study a broad range of infectious diseases, including hepatitis viruses A, B, and C, chlamydia, gonorrhoeae, human papillomavirus (HPV), herpesviruses, and coronaviruses. From the outset, the ACS has adopted a multidisciplinary approach, examining the prevalence and incidence of infections, their determinants, and their natural history and pathogenesis. The long-term collection of sexual behaviour data is a key strength of the ACS, enabling in-depth analyses of behavioural trends over time.
ACS for researchers
The ACS is a longitudinal study with >40 years of follow-up. The data and material collection is large and offers many opportunities for research. The ACS team enjoys working with scientists all over the world. On this page you will find how to work together with the ACS and we provide information on our study protocol and data collection.
ACS for participants
Scientifically, the ACS has been highly successful, largely due to the exceptional commitment of its participants, who visit the study every six months. We are deeply grateful for this long-standing engagement: some participants have been involved for over 40 years. Each year, new participants join while others leave, reflecting the dynamic nature of the cohort. Participation in the ACS is voluntary, and participants may withdraw at any time. The ACS aims to remain a good reflection of the MSM community in Amsterdam.
Publications with ACS data
The ACS publishes peer-reviewed scientific articles, PhD theses and yearly reports. Since the start of the ACS, more than 300 articles and 50 theses have been published.
