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About the Amsterdam Cohort Study

The Amsterdam Cohort Study (ACS) on HIV/AIDS and other blood-borne infections (BBI), sexually transmittable infections (STI) and other infections is a prospective observational cohort study. The ACS among men who have sex with men (MSM) started in 1984. In 1985, the study was expanded to include people who use drugs (PWUD).


Early on, research focused on HIV/AIDS. Later, the study was broadened to include research on hepatitis viruses A,B, and C, Chlamydia, gonorrhoeae, human papillomavirus (HPV), herpesviruses, coronaviruses, etc. From the outset, research within the ACS has taken a multidisciplinary approach. The ACS investigates the prevalence and incidence of infections, associated determinants and the natural course and pathogenesis of these infections.

ACS for researchers

The ACS is a longitudinal study with >35 years of follow-up. The data and material collection is large and offers many opportunities for research. The ACS team enjoys working with scientists all over the world. On this page you will find how to work together with the ACS and we provide information on our study protocol and data collection.

ACS for participants

Scientifically, the ACS is a very successful study. This is due to its highly commitment participants who visit the study every 6 months. We are grateful for their commitment. Some participants have been participating since that start of the study. Every year new people join the study and some participants leave. Participation is voluntary and you can stop at any time. The ACS aims to be a good reflection of the MSM community in Amsterdam.

ACS Publications

The ACS publishes peer-reviewed scientific articles, theses and year reports. Since the start of the ACS, more than XXX articles and XXX theses have been published. Open-access data is available for educational purposes. 

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